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20 years of advancing rigorous science

20 years of advancing rigorous science

Explore open access research that connects methods, disciplines, and researchers worldwide.

Since 2006, PLOS One has helped researchers share rigorous open science with the world, bringing together a global collection of research shaped by strong methods, high ethical standards, and transparency.

By prioritizing scientific validity, ethical practice, and reproducibility over perceived novelty, we enable research to be shared, examined, and built on by researchers across disciplines and around the world.

Our commitment to ethical, reproducible research

In this short video, we show how editorial screening, peer review, and post‑publication checks work together to uphold the integrity of published research.

Learn more about research integrity and publication ethics at PLOS.

Research with real‑world impact

From advancing human health to understanding global ecosystems, we publish rigorously conducted, multidisciplinary research that shapes fields, methods, and practice.

Explore recent insights from our research community that connect real‑world questions with evidence‑based investigation.

Tracking global ocean plastic pollution

Understanding the scale of ocean plastic pollution depends on long‑term, global evidence. New datasets are refining estimates and revealing patterns in how plastic accumulates and changes over time.

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Growing food on Mars: what experiments reveal about agricultural feasibility

Assessing whether crops can establish in Mars‑relevant conditions depends on how plants respond to soils, water, and cultivation systems under controlled inputs. Experimental datasets are clarifying how crops respond under controlled growing conditions.

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People‑centered cancer research: the value of individuality

Cancer research is increasingly recognizing that individual experience and context matter. People‑centered approaches are prompting new ways of thinking about how cancer evidence is generated and interpreted.

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Research that sparks discussion

Explore 20 studies that have sparked discussion within and beyond the research community, spanning climate science, public health, behavior, neuroscience, and environmental research.

Considering ecological traits of fishes to understand microplastic ingestion across Pacific coastal fisheries

Age-related changes in gait, balance, and strength parameters: A cross-sectional study

Dogs can discriminate between human baseline and psychological stress condition odours

A large-scale experiment on New Year’s resolutions: Approach-oriented goals are more successful than avoidance-oriented goals

A double-edged hashtag: Evaluation of #ADHD-related TikTok content and its associations with perceptions of ADHD

The Myth of Man the Hunter: Women’s contribution to the hunt across ethnographic contexts

Red seaweed (Asparagopsis taxiformis) supplementation reduces enteric methane by over 80 percent in beef steers

Understanding climate change from a global analysis of city analogues

Anthropogenic contamination of tap water, beer, and sea salt

Twelve Weeks of Sprint Interval Training Improves Indices of Cardiometabolic Health Similar to Traditional Endurance Training despite a Five-Fold Lower Exercise Volume and Time Commitment

The Importance of the Secure Base Effect for Domestic Dogs – Evidence from a Manipulative Problem-Solving Task

Why Do Woodpeckers Resist Head Impact Injury: A Biomechanical Investigation

How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data

Resistance Exercise Reverses Aging in Human Skeletal Muscle

More than 75 percent decline over 27 years in total flying insect biomass in protected areas

Low 2012–13 Influenza Vaccine Effectiveness Associated with Mutation in the Egg-Adapted H3N2 Vaccine Strain Not Antigenic Drift in Circulating Viruses

Large Aggregates Are the Major Soluble Aβ Species in AD Brain Fractionated with Density Gradient Ultracentrifugation

New Horned Dinosaurs from Utah Provide Evidence for Intracontinental Dinosaur Endemism

Social Waves in Giant Honeybees Repel Hornets

The Effectiveness of Contact Tracing in Emerging Epidemics

Explore more articles

	Anthropogenic contamination of tap water, beer, and sea salt		More than 75 percent decline over 27 years in total flying insect biomass in protected areas
	Twelve Weeks of Sprint Interval Training Improves Indices of Cardiometabolic Health Similar to Traditional Endurance Training despite a Five-Fold Lower Exercise Volume and Time Commitment		Low 2012–13 Influenza Vaccine Effectiveness Associated with Mutation in the Egg-Adapted H3N2 Vaccine Strain Not Antigenic Drift in Circulating Viruses
	The Importance of the Secure Base Effect for Domestic Dogs – Evidence from a Manipulative Problem-Solving Task		Large Aggregates Are the Major Soluble Aβ Species in AD Brain Fractionated with Density Gradient Ultracentrifugation
	Why Do Woodpeckers Resist Head Impact Injury: A Biomechanical Investigation		New Horned Dinosaurs from Utah Provide Evidence for Intracontinental Dinosaur Endemism
	How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data		Social Waves in Giant Honeybees Repel Hornets
	Resistance Exercise Reverses Aging in Human Skeletal Muscle		The Effectiveness of Contact Tracing in Emerging Epidemics

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